Formulation, Characterization and Stability Evaluation of Antidiabetic Poly Herbal Suspensions
| Vol-3 | Issue-12 | December 2018 | Published Online: 10 December 2018 PDF ( 743 KB ) | ||
| Author(s) | ||
| Vipul Agarwal 1; Vijender Singh 2 | ||
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1School of Pharmacy, Monad University, KastalaKasmabad, 245304, Uttar Pradesh, India 2School of Pharmacy, Sharda University, Greater Noida, 201310, Uttar Pradesh, India |
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| Abstract | ||
From the time immortal, herbal combination formulations are also used as herbal therapies for different illnesses, including diabetes. The aim of the current study were to formulateand evaluate polyherbal suspensions using dried Hydroalcoholic extracts of dried seeds of Syzygiumcumini, dried fruit ofMomordicacharantia Linn, dried leaves of Gymnemasylvestre and heartwood of Pterocarpus marsupium. All the plants are regarded as active anti-diabetic behaviour in ancient Indian literature / folklore.Polyherbal suspensions were formulated using a suspending agent and other excipients.All formulations were further characterized for colour, pH, viscosity, sedimentation ratio, redispersibility, particle size, crystal formation, zeta potential, TLC profile and stability tests. The findings showed that the suspension was free flow and quickly dispersible.The organoleptic and physicochemical properties were satisfactory. From these findings it can be suggested that the herbal suspensions PHFA-6 in the sample were physically and chemically stable out of all the prepared formulations.Thus, the prepared oral herbal suspension is safe for use with promising hypoglycemic activity. |
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| Keywords | ||
| Syzygiumcumini, Momoridicacharantia, Gymnemasylvestre, Pterocarpusmarsupium, polyherbal formulation and hypoglycemic activity. | ||
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