Effect of Keelvayu Nivarana Churunam (KNC) Extract on Glycoproteins in Complete Freund’s Adjuvant (CFA) induced Arthritic Rats

Glycoproteins are important groups of compounds involved in the cellular function. They play a significant role in contributing to the surface properties of the cells and also important role in tumorigenesis and as mediators of immunological specificity. Carbohydrates moieties of glycoproteins have also been implicated in the transport of metabolites across cell membranes and also observed a direct relationship between glycolproteins and tumorigenesis. In the present study to evaluate the Keelvayu Nivarana Churunam (KNC) on glycoproteins as hexose, hexosamine and sialic acid in the plasma against CFA induced arthritis in albino rats. This study shows that KNC extract administration decrease the glycoprotein synthesis in arthritic rats. This may be due to the inhibitory action of KNC extract and offer promise as potential antiarthritic agent against CFA treated rats.