Synthesis, characterization and antimicrobial screening of some novel chalcones and their derivative
| Vol-4 | Issue-01 | January-2019 | Published Online: 10 January 2019 PDF ( 375 KB ) | ||
| Author(s) | ||
| D. W. Shinde 1; P. S. Mahajan 2; S. S. Bhagat 3; C. H. Gill 4 | ||
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1Department of Chemistry, Dr. Babasaheb Ambedkar Marathwada University, Aurangabad- 431 004 (India) 2Department of Chemistry, Dr. Babasaheb Ambedkar Marathwada University, Aurangabad- 431 004 (India) 3Department of Chemistry, R. B. Attal Arts, Science and Commerce College, Georai, Beed-431127 (India) 4Department of Chemistry, Dr. Babasaheb Ambedkar Marathwada University, Aurangabad- 431 004 (India) |
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| Abstract | ||
Synthesis of some novel 2-(4-(4-fluorophenylthio) phenyl)-4H-chromen-4-one 6a-h and 2-(4-(4-fluorophenylthio)phenyl)-3-chloro-4H-chromen-4-one 7a-h by oxidative cyclization of (E)-3-(4-(4-fluorophenylthio)phenyl)-1-(2-hydroxyphenyl)prop-2-en-1-one 5a-h using DMSO/I2 and DMSO/CuCl2 at reflux condition has been carried out. The synthesized compounds have been characterized by melting point, FT-IR, NMR and EI-MS spectral data. All the newly synthesized derivatives have been evaluate. |
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| Keywords | ||
| Chalcone, Chromone, Chlorochromone, Antibacterial activity, Antifungal activity | ||
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